Blog & Media

Blog & Media

Sims IVF trial receptivity test

Wednesday, 18th September 2013 | 0 comments
Today we discussed a patient with good quality expanding blastocysts who, unexpectedly, is not getting pregnant following implantation. 

Male infertility and nutritional interventions

Monday, 16th September 2013 | 0 comments
At Sims IVF, we were delighted to welcome the renowned nutritional biologist and author Dr Marilyn Glenville to the Clinic today for a talk on male Infertility and nutritional interventions. 

Neupogen and Implantation

Thursday, 5th September 2013 | 0 comments
G-CSF (granulocyte colony stimulating factor) is a natural cytokine (chemical messenger) which is normally found in the body, and neupogen (filgrastim) is a synthetic (recombinant) form of G-CSF . Higher levels of natural G-CSF seem to be found in follicles which go on to produce healthy eggs compared to follicles which produce poor eggs. Higher levels of G-CSF are expressed in healthy embryos and in healthy placenta, so it is a marker of embryonic/placental viability that seems to have a role in communicating with the endometrium to allow implantation.   It is suggested that it may improve lining thickness and egg quality (although the number of patients he has tried it out on for egg quality is apparently very small), as well as placental growth and may permit a successful live birth for ladies who have failed to respond to IVIG.  For patients who respond well to it, he believes it can replace IVIG.

Natural killer cells in pregnancy and recurrent miscarriage

Friday, 12th July 2013 | 0 comments
Today Dr Bart gave a general lecture on the role of natural killer cells in pregnancy and recurrent miscarriage.  Needless to say this is a very complex area involving diverse HLA receptors, adhesion molecules & cytokines. We are developing new modalities to address these – we will bring you further news on these developments as soon as we can.

Proposal for pilot programme at Sims IVF

Friday, 12th July 2013 | 0 comments
Today the medical team were joined by a visiting physician from INVIMED in Poland. Our discussions focussed on the recent ESHRE meeting, which took place in London over the last few days. 

Management of Miscarriage and Ectopic Pregnancies

Thursday, 4th July 2013 | 0 comments
This week, our team has discussed new guidelines for the management of miscarriage and ectopic pregnancies.  Thankfully ectopic pregnancies are a relatively rare occurrence, but they do require swift and decisive action.   We discussed the case of a patient with multiple failed cycles, two at Sims and two elsewhere. Our new FMR 1 test showed up a low, norm allele ratio on the fragile X gene so we can now counsel this patient that she needs a specifically modified protocol (with more embryos transferred), to match the normal chances of successful pregnancy.  In addition, her stress markers were high, so a three month break with DHEA supplementation was recommended. Dr. David Walsh, MRCOGSims IVF

Eeva success in Ireland

Monday, 20th May 2013 | 0 comments
Preliminary audit of the first cases of time lapse selection tool utilising the Eeva system at Sims IVF has confirmed recently published results from a British study (below).Our audit of Eeva completed this year confirms the major benefits of Eeva in selecting viable embryos. 55% of our patients who had one or more embryos with high implantation potential by Eeva achieved a pregnancy.The British study focused on the transfer of blastocyst embryos, and quite remarkably in the Irish population, all of our Sims patients with one or more either high implantation Eeva embryos transferred at the blastocyst stage achieved a pregnancy.This preliminary assessment in an Irish population confirms the major benefits of Eeva selection in identifying those patients with the best chances of achieving pregnancy and maximising their chance of conceiving.The message for us as clinicians at Sims is that we need to be much more proactive in combining the structural benefits of assessment at the blastocyst stage with the functional assessments of the genetic potential of the embryo with the Eeva timelapse selection tool.This combination of technologies in our hands results in an extremely high chance of pregnancy. We are continuing further investigations to further establish the benefits of Eva selection in routine IVF practice.

Sims IVF featured in Easy Parenting

Monday, 13th February 2012 | 0 comments
Ann Bracken, Mind/Body Programme facilitator and Fertility Counsellor discusses the benefits of taking an integrative approach to managing stress in fertility treatment in Easy Parenting Magazine

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